Regulatory Status
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Safety Data
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Expert Verdict
TGF-β1 is involved in fibrotic pathways and has immunomodulatory activity — theoretical safety concern if absorbed systemically; produced in *E. coli* via fermentation (vegan-compatible)
Frequently Asked Questions
Is rh-Polypeptide-22 safe in cosmetics?
TGF-β1 is involved in fibrotic pathways and has immunomodulatory activity — theoretical safety concern if absorbed systemically; produced in *E. coli* via fermentation (vegan-compatible) The EU classifies rh-Polypeptide-22 as "permitted". Safety rating: MODERATE.
Is rh-Polypeptide-22 allowed in the EU?
rh-Polypeptide-22 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does rh-Polypeptide-22 do in cosmetics?
rh-Polypeptide-22 functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Corresponds to TGF-β1 (typical CAS: 80693-00-1 for recombinant form).
What is the Margin of Safety for rh-Polypeptide-22?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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