Rhamnus Purshiana Bark Extract

INCI: RHAMNUS PURSHIANA BARK EXTRACT

CAS Number
84650-55-5
Function
Perfuming Agent, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted for cosmetic use; FDA removed cascara sagrada from OTC laxative approval in 2002 (medicinal context only)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains hydroxyanthracene derivatives (anthraquinones) โ€” potential genotoxicity concern; oral use restricted by EMA; cosmetic use should be at low concentrations

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Concern Level: High

Regulatory Flags

plant-extract fragrance-component

Frequently Asked Questions

Is Rhamnus Purshiana Bark Extract safe in cosmetics?

Contains hydroxyanthracene derivatives (anthraquinones) โ€” potential genotoxicity concern; oral use restricted by EMA; cosmetic use should be at low concentrations The EU classifies Rhamnus Purshiana Bark Extract as "permitted". Safety rating: MODERATE.

Is Rhamnus Purshiana Bark Extract allowed in the EU?

Rhamnus Purshiana Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rhamnus Purshiana Bark Extract do in cosmetics?

Rhamnus Purshiana Bark Extract functions as: Perfuming Agent, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84650-55-5.

What is the Margin of Safety for Rhamnus Purshiana Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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