Salvadora Persica Bark/Root Extract
INCI: SALVADORA PERSICA BARK/ROOT EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Salvadora Persica Bark/Root Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 2.5 mg/kg bw/day | oral | mouse | Subchronic | COSMOS_DB |
| NOAEL | 2.5 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 400 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 0.02 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 20000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 10000 mg/kg bw/day | oral | monkey | Chronic | COSMOS_DB |
| NOAEL | 5000 mg/kg bw/day | oral | monkey | Chronic | COSMOS_DB |
| NOAEL | 7500 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 10000 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
Expert Verdict
None identified; contains bioactive compounds with antioxidant and anti-inflammatory properties
Regulatory Flags
Frequently Asked Questions
Is Salvadora Persica Bark/Root Extract safe in cosmetics?
None identified; contains bioactive compounds with antioxidant and anti-inflammatory properties The EU classifies Salvadora Persica Bark/Root Extract as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Salvadora Persica Bark/Root Extract allowed in the EU?
Salvadora Persica Bark/Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Salvadora Persica Bark/Root Extract do in cosmetics?
Salvadora Persica Bark/Root Extract functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 8007-40-7.
What is the Margin of Safety for Salvadora Persica Bark/Root Extract?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Salvadora Persica Bark/Root Extract?
The NOAEL (No Observed Adverse Effect Level) for Salvadora Persica Bark/Root Extract is 2.5 mg/kg bw/day based on a Subchronic study via oral route in mouse. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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