Atropa Belladonna Root Extract

INCI: ATROPA BELLADONNA ROOT EXTRACT

CAS Number
8007-93-0
Function
skin-conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Belladonna alkaloids (atropine, scopolamine, hyoscyamine) are controlled drug substances. FDA has issued multiple safety warnings about belladonna in consumer products. No CIR safety assessment exists for cosmetic use.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU cosmetics (Annex II, Regulation EC 1223/2009) and effectively prohibited in US due to controlled alkaloid content. Highly toxic plant extract containing tropane alkaloids (atropine, scopolamine, hyoscyamine) with confirmed dermal absorption causing anticholinergic toxidrome. No safe concentration established for cosmetic use.

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Concern Level: High

Regulatory Flags

eu-prohibited systemic-toxicity tropane-alkaloids anticholinergic dermal-absorption-confirmed no-safe-dose no-cir-assessment fda-warnings controlled-substance-alkaloids do-not-use eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Atropa Belladonna Root Extract safe in cosmetics?

Prohibited in EU cosmetics (Annex II, Regulation EC 1223/2009) and effectively prohibited in US due to controlled alkaloid content. Highly toxic plant extract containing tropane alkaloids (atropine, scopolamine, hyoscyamine) with confirmed dermal absorption causing anticholinergic toxidrome. No safe concentration established for cosmetic use. The EU classifies Atropa Belladonna Root Extract as "prohibited". Safety rating: POOR.

Is Atropa Belladonna Root Extract allowed in the EU?

Atropa Belladonna Root Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Atropa Belladonna Root Extract do in cosmetics?

Atropa Belladonna Root Extract functions as: skin-conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 8007-93-0.

What is the Margin of Safety for Atropa Belladonna Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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