Salvia Officinalis Leaf Extract

INCI: SALVIA OFFICINALIS LEAF EXTRACT

CAS Number
84082-79-1
Function
Skin conditioning, anti-seborrheic, cleansing, oral care, tonic, antioxidant, antimicrobial
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS as essential oil, oleoresin, and natural extractive under 21 CFR 182.20 and 182.10. Sage oil ruled inadequate for OTC astringent GRASE (21 CFR 310.545). No cosmetic restrictions. CIR concluded safe when formulated to be non-sensitizing (Final Report 2022). Max reported use in US VCRP: 0.38% in skin care (213 formulations).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CAS 84082-79-1 (EINECS 282-025-9). EU: permitted without concentration limits under Regulation (EC) No 1223/2009, not on Annex II, III, V, or VI; indirect thujone restriction via IFRA 49th Amendment. No dedicated SCCS opinion. US: GRAS under 21 CFR 182.20 and 182.10. CIR Panel (June 2022) concluded safe in cosmetics at present use concentrations when formulated to be non-sensitizing.

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Concern Level: Low

Regulatory Flags

thujone-content no-mos-calculable no-dermal-absorption-data estrogenic-potential terpene-sensitizer-risk aggregate-exposure-tracking-required

Frequently Asked Questions

Is Salvia Officinalis Leaf Extract safe in cosmetics?

CAS 84082-79-1 (EINECS 282-025-9). EU: permitted without concentration limits under Regulation (EC) No 1223/2009, not on Annex II, III, V, or VI; indirect thujone restriction via IFRA 49th Amendment. No dedicated SCCS opinion. US: GRAS under 21 CFR 182.20 and 182.10. CIR Panel (June 2022) concluded safe in cosmetics at present use concentrations when formulated to be non-sensitizing. The EU classifies Salvia Officinalis Leaf Extract as "permitted". Safety rating: GOOD.

Is Salvia Officinalis Leaf Extract allowed in the EU?

Salvia Officinalis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Salvia Officinalis Leaf Extract do in cosmetics?

Salvia Officinalis Leaf Extract functions as: Skin conditioning, anti-seborrheic, cleansing, oral care, tonic, antioxidant, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 84082-79-1.

What is the Margin of Safety for Salvia Officinalis Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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