Salvia Officinalis (Sage) Leaf Oil

INCI: SALVIA OFFICINALIS (SAGE) LEAF OIL

CAS Number
84082-79-1 (generic); 8022-56-8 (generic); 84776-73-8 (generic)
Function
Fragrance ingredient, skin conditioning agent, tonic
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.1%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS (21 CFR ยง182.20); acute oral LD50 = 2600 mg/kg in rats

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Thujone neurotoxicity (8โ€“33% thujone in oil per IFRA); classified "irritating to skin" or "corrosive" when tested neat on RhE tissues; camphor and thujone levels must be controlled; IFRA category-specific limits apply

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Concern Level: Moderate

Regulatory Flags

plant-oil fragrance-component

Frequently Asked Questions

Is Salvia Officinalis (Sage) Leaf Oil safe in cosmetics?

Thujone neurotoxicity (8โ€“33% thujone in oil per IFRA); classified "irritating to skin" or "corrosive" when tested neat on RhE tissues; camphor and thujone levels must be controlled; IFRA category-specific limits apply The EU classifies Salvia Officinalis (Sage) Leaf Oil as "restricted". Safety rating: GOOD.

Is Salvia Officinalis (Sage) Leaf Oil allowed in the EU?

Salvia Officinalis (Sage) Leaf Oil EU regulatory status: restricted. Maximum allowed concentration: 0.1%. This is based on EU Regulation 1223/2009 and its amendments.

What does Salvia Officinalis (Sage) Leaf Oil do in cosmetics?

Salvia Officinalis (Sage) Leaf Oil functions as: Fragrance ingredient, skin conditioning agent, tonic. It is classified as a cosmetic ingredient in our database. CAS number: 84082-79-1 (generic); 8022-56-8 (generic); 84776-73-8 (generic).

What is the Margin of Safety for Salvia Officinalis (Sage) Leaf Oil?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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