Salvia Rosmarinus Leaf Oil
INCI: ROSMARINUS OFFICINALIS (ROSEMARY) LEAF OIL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
8 study endpoints found for Salvia Rosmarinus Leaf Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| dose_tested | 200 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| dose_tested | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| dose_tested | 130 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| dose_tested | 1500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Allergen declaration mandatory. Chemotype matters — camphor, cineole, and verbenone chemotypes have different safety profiles. Keep peroxide value low; oxidized oil is significantly more sensitizing
Regulatory Flags
Frequently Asked Questions
Is Salvia Rosmarinus Leaf Oil safe in cosmetics?
Allergen declaration mandatory. Chemotype matters — camphor, cineole, and verbenone chemotypes have different safety profiles. Keep peroxide value low; oxidized oil is significantly more sensitizing The EU classifies Salvia Rosmarinus Leaf Oil as "permitted". Safety rating: GOOD. 8 toxicological study endpoint(s) are available in our database.
Is Salvia Rosmarinus Leaf Oil allowed in the EU?
Salvia Rosmarinus Leaf Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Salvia Rosmarinus Leaf Oil do in cosmetics?
Salvia Rosmarinus Leaf Oil functions as: Perfuming, masking, skin conditioning, tonic, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84604-14-8.
What is the Margin of Safety for Salvia Rosmarinus Leaf Oil?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Salvia Rosmarinus Leaf Oil?
The NOAEL (No Observed Adverse Effect Level) for Salvia Rosmarinus Leaf Oil is 200 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 8 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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