SH-Decapeptide-3 Amide

INCI: SH-DECAPEPTIDE-3 AMIDE

CAS Number
Not assigned
Function
Skin conditioning (amidated C-terminus variant of SH-Decapeptide-3 — amidation typically enhances stability and receptor binding)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific restriction; permitted under general cosmetic provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Amidation may slightly increase bioactivity compared to parent peptide — verify supplier stability and efficacy data

⚠️
Concern Level: Low

Frequently Asked Questions

Is SH-Decapeptide-3 Amide safe in cosmetics?

Amidation may slightly increase bioactivity compared to parent peptide — verify supplier stability and efficacy data The EU classifies SH-Decapeptide-3 Amide as "permitted". Safety rating: GOOD.

Is SH-Decapeptide-3 Amide allowed in the EU?

SH-Decapeptide-3 Amide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does SH-Decapeptide-3 Amide do in cosmetics?

SH-Decapeptide-3 Amide functions as: Skin conditioning (amidated C-terminus variant of SH-Decapeptide-3 — amidation typically enhances stability and receptor binding). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for SH-Decapeptide-3 Amide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is SH-Decapeptide-3 Amide in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for SH-Decapeptide-3 Amide in your formulation.