SH-Nonapeptide-1

INCI: SH-NONAPEPTIDE-1

CAS Number
Not publicly assigned for SH- variant (parent Nonapeptide-1: 158563-45-2)
Function
Skin conditioning ; parent Nonapeptide-1 functions as melanin synthesis inhibitor / skin brightening
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; however, skin-lightening claims may invoke FDA scrutiny under OTC monograph considerations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Skin-brightening/whitening claims are heavily regulated in many markets (EU, ASEAN); ensure claims comply with local regulations; verify the SH- prefix variant's sequence against parent Nonapeptide-1

โš ๏ธ
Concern Level: Low

Frequently Asked Questions

Is SH-Nonapeptide-1 safe in cosmetics?

Skin-brightening/whitening claims are heavily regulated in many markets (EU, ASEAN); ensure claims comply with local regulations; verify the SH- prefix variant's sequence against parent Nonapeptide-1 The EU classifies SH-Nonapeptide-1 as "permitted". Safety rating: GOOD.

Is SH-Nonapeptide-1 allowed in the EU?

SH-Nonapeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does SH-Nonapeptide-1 do in cosmetics?

SH-Nonapeptide-1 functions as: Skin conditioning ; parent Nonapeptide-1 functions as melanin synthesis inhibitor / skin brightening. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for SH- variant (parent Nonapeptide-1: 158563-45-2).

What is the Margin of Safety for SH-Nonapeptide-1?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is SH-Nonapeptide-1 in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for SH-Nonapeptide-1 in your formulation.