sh-Octapeptide-3

INCI: SH-OCTAPEPTIDE-3

CAS Number
Not publicly assigned
Function
Bleaching / Skin Lightening
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Skin lightening claims may trigger OTC drug classification under FDA. Cosmetic use permitted if no drug claims are made

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

The bleaching/depigmenting function is the key flag. In the US, skin lightening products are regulated as OTC drugs. In the EU, the ingredient itself is not restricted but product claims must be managed. Ensure no tyrosinase inhibition mechanism conflicts with restricted substances

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Concern Level: Moderate

Frequently Asked Questions

Is sh-Octapeptide-3 safe in cosmetics?

The bleaching/depigmenting function is the key flag. In the US, skin lightening products are regulated as OTC drugs. In the EU, the ingredient itself is not restricted but product claims must be managed. Ensure no tyrosinase inhibition mechanism conflicts with restricted substances The EU classifies sh-Octapeptide-3 as "permitted". Safety rating: MODERATE.

Is sh-Octapeptide-3 allowed in the EU?

sh-Octapeptide-3 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does sh-Octapeptide-3 do in cosmetics?

sh-Octapeptide-3 functions as: Bleaching / Skin Lightening. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.

What is the Margin of Safety for sh-Octapeptide-3?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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