sh-Polypeptide-28

INCI: SH-POLYPEPTIDE-28

CAS Number
Not publicly assigned
Function
Skin conditioning; recombinant human peptide — growth factor analog
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted cosmetic ingredient; no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited published toxicological data specific to this variant; growth factor class precautions apply

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is sh-Polypeptide-28 safe in cosmetics?

Limited published toxicological data specific to this variant; growth factor class precautions apply The EU classifies sh-Polypeptide-28 as "permitted". Safety rating: GOOD.

Is sh-Polypeptide-28 allowed in the EU?

sh-Polypeptide-28 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does sh-Polypeptide-28 do in cosmetics?

sh-Polypeptide-28 functions as: Skin conditioning; recombinant human peptide — growth factor analog. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.

What is the Margin of Safety for sh-Polypeptide-28?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is sh-Polypeptide-28 in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for sh-Polypeptide-28 in your formulation.