sh-Polypeptide-7 sh-Oligopeptide-1
INCI: SH-POLYPEPTIDE-7 SH-OLIGOPEPTIDE-1 (COMBINATION INCI — LISTED AS A SINGLE ENTRY IN COSING)
Regulatory Status
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Safety Data
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Expert Verdict
🔴 EGF (sh-Oligopeptide-1) is flagged in multiple jurisdictions for potential tumorigenic concerns — EGF receptor overactivation is implicated in cancer biology. Combined with hGH fragment, this is the highest-risk combination on this list. Some countries (e.g., South Korea) have debated restricting EGF in cosmetics. Requires careful claim management and risk assessment
Frequently Asked Questions
Is sh-Polypeptide-7 sh-Oligopeptide-1 safe in cosmetics?
🔴 EGF (sh-Oligopeptide-1) is flagged in multiple jurisdictions for potential tumorigenic concerns — EGF receptor overactivation is implicated in cancer biology. Combined with hGH fragment, this is the highest-risk combination on this list. Some countries (e.g., South Korea) have debated restricting EGF in cosmetics. Requires careful claim management and risk assessment The EU classifies sh-Polypeptide-7 sh-Oligopeptide-1 as "permitted". Safety rating: MODERATE.
Is sh-Polypeptide-7 sh-Oligopeptide-1 allowed in the EU?
sh-Polypeptide-7 sh-Oligopeptide-1 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does sh-Polypeptide-7 sh-Oligopeptide-1 do in cosmetics?
sh-Polypeptide-7 sh-Oligopeptide-1 functions as: Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned as a complex; sh-Oligopeptide-1 individually has CAS 96827-07-5 (rh-EGF).
What is the Margin of Safety for sh-Polypeptide-7 sh-Oligopeptide-1?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check sh-Polypeptide-7 sh-Oligopeptide-1 compliance across multiple jurisdictions:
Related Ingredients
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