Sodium Butyroyl Hyaluronate

INCI: SODIUM BUTYROYL HYALURONATE

CAS Number
942471-70-7
Function
Humectant, skin conditioning, antioxidant, anti-inflammatory — HA derivative with butyric acid esterification for enhanced lipophilicity and enzyme resistance
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; no restrictions; hyaluronic acid derivatives are widely used in US cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Minimal; premium ingredient with strong safety profile. Ensure supplier provides certificate confirming biotech-origin HA (not animal-derived) for COSMOS/vegan compliance. Residual butyric acid odor should be verified as eliminated in final grade

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Concern Level: None

Frequently Asked Questions

Is Sodium Butyroyl Hyaluronate safe in cosmetics?

Minimal; premium ingredient with strong safety profile. Ensure supplier provides certificate confirming biotech-origin HA (not animal-derived) for COSMOS/vegan compliance. Residual butyric acid odor should be verified as eliminated in final grade The EU classifies Sodium Butyroyl Hyaluronate as "permitted". Safety rating: EXCELLENT.

Is Sodium Butyroyl Hyaluronate allowed in the EU?

Sodium Butyroyl Hyaluronate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Butyroyl Hyaluronate do in cosmetics?

Sodium Butyroyl Hyaluronate functions as: Humectant, skin conditioning, antioxidant, anti-inflammatory — HA derivative with butyric acid esterification for enhanced lipophilicity and enzyme resistance. It is classified as a cosmetic ingredient in our database. CAS number: 942471-70-7.

What is the Margin of Safety for Sodium Butyroyl Hyaluronate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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