Sodium Cholesteryl Sulfate

INCI: SODIUM CHOLESTERYL SULFATE

Sodium Cholesteryl Sulfate (CAS 2864-50-8) is a cosmetic cosmetic ingredient functioning as Skin conditioning, emulsifying, skin barrier repair (component of natural skin. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 2864-50-8 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, emulsifying, skin barrier repair (component of natural skin lipids)
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
C27H45NaO4S
MW
488.7 g/mol
PubChem CID
23679068
IUPAC Name
sodium [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] sulfate
InChIKey
LMPVQXVJTZWENW-KPNWGBFJSA-M

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted under general cosmetic ingredient provisions; recognized as skin-identical lipid

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Cholesteryl Sulfate.

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Sodium Cholesteryl Sulfate.

Chemical Function

Softener and conditioner

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL4475544
View full pharmaceutical profile →

Frequently Asked Questions

Is Sodium Cholesteryl Sulfate safe in cosmetics?

Sodium Cholesteryl Sulfate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Sodium Cholesteryl Sulfate allowed in the EU?

Sodium Cholesteryl Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Cholesteryl Sulfate do in cosmetics?

Sodium Cholesteryl Sulfate functions as: Skin conditioning, emulsifying, skin barrier repair (component of natural skin lipids). It is classified as a cosmetic ingredient in our database. CAS number: 2864-50-8.

Is Sodium Cholesteryl Sulfate used outside cosmetics?

Sodium Cholesteryl Sulfate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Related Ingredients

Almond Oil Glycereth-8 Esters
Excellent Same category
Emollient; emulsifying; skin conditio...
Almond Oil PEG-8 Esters
Excellent Same category
Emollient; emulsifying; skin conditio...
Argan Oil Polyglyceryl-6 Esters
Excellent Same category
Emollient, emulsifying, skin conditio...
Beheneth-2
Excellent Same category
Emulsifying (co-emulsifier, W/O suppo...
Brassica Glycerides
Excellent Same category
Emollient, Co-emulsifier, Viscosity A...
C12-16 Alcohols
Excellent Same category
Emollient; Emulsifier; Viscosity incr...
1-Methylhydantoin-2-imide (Creatinine)
Excellent Similar safety
Skin conditioning (skin brightening/l...
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent Similar safety
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent Similar safety
Fragrance (rich woody, orris/iris roo...
2-Hydroxypropylcarbamato Amodimethicone
Excellent Similar safety
Hair conditioning; modified aminosili...
2-O-Ethyl Ascorbic Acid
Excellent Similar safety
Softener and conditioner
3 O Ethyl Ascorbic Acid
Excellent Similar safety
Antioxidant; tyrosinase inhibitor; me...
SODIUM (ASTROCARYUM VULGARE/EUTERPE OLERACEAE/PALM) FRUIT/(ASTROCARYUM VULGARE/PALM) KERNEL/(ASTROCARYUM MURUMURU/BABASSU/BERTHOLLETIA EXCELSA/CARAPA GUIANENSIS/COCOA/FEVILLEA TRILOBATA/PASSIFLORA EDULIS/THEOBROMA GRANDIFLORUM) SEEDATE
Good Browse nearby
Cleansing, Surfactant - Cleansing
SODIUM BEHENOYL/COCOYL (ALANINE/ARGININE/ASPARAGINE/ASPARTIC ACID/GLUTAMIC ACID/GLYCINE/ISOLEUCINE/LEUCINE/LYSINE/METHIONINE/PHENYLALANINE/PROLINE/SERINE/THREONINE/TRYPTOPHAN/TYROSINE/VALINE)
Good Browse nearby
Cleansing, Emulsion Stabilising, Surf...
SODIUM BEHENOYL/COCOYL (ARGININE/GLUTAMIC ACID/ISOLEUCINE/LEUCINE/LYSINE/PHENYLALANINE/PROLINE/THREONINE/VALINE)
Good Browse nearby
Cleansing, Surfactant - Cleansing, Su...

Is Sodium Cholesteryl Sulfate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Cholesteryl Sulfate in your formulation.