Is Sodium Cyclamate safe in cosmetics?
Sodium Cyclamate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: prohibited.
MODERATE
Cosmetic Ingredient
Sodium Cyclamate
Also known as: Cyclamate, sodium, Assurgrin feinsuss, Assurgrin vollsuss, Cyclamate, sodium salt, Cyclamic acid sodium salt (+15 more)
INCI: SODIUM CYCLAMATE (PRIMARILY A FOOD ADDITIVE, E952)
Sodium Cyclamate (CAS 139-05-9) is a cosmetic cosmetic ingredient functioning as Artificial sweetener — not a standard cosmetic functional ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
Function
Artificial sweetener — not a standard cosmetic functional ingredient
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
sodium N-cyclohexylsulfamate
InChIKey
UDIPTWFVPPPURJ-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
prohibited
US Notes
Prohibited in food (banned 1969) — not approved for cosmetic use either
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Cyclamate.
Calculate MoS for your specific formulation with the MoS Calculator.
IARC Carcinogenicity
International Agency for Research on Cancer (WHO) monograph evaluation.
IARC Group
3
Volume
Sup 7, 73
Evaluation Year
1998
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
Cyclamates (sodium cyclamate) | Group 3: Not classifiable as to its carcinogenicity to humans | Volume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987; 440 pages; ISBN 92-832-1411-0 (out of print) | Volume 73: (1999) Some Chemicals that Cause Tumours of the Kidney or Urinary Bladder in Rodents and Some Other Substances
Source: International Agency for Research on Cancer (IARC)
Regulatory (1)
JECFA Evaluation
SODIUM CYCLAMATE | 1982 | 0-11 mg/kg bw | CYCLAMATES ADI EXPRESSED AS CYCLAMIC ACID | TRS 683-JECFA 26/27 | FAS 17-JECFA 26/66
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for Sodium Cyclamate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fda_food_additive
Known Synonyms
Cyclamate, sodium
Assurgrin feinsuss
Assurgrin vollsuss
Cyclamate, sodium salt
Cyclamic acid sodium salt
Cyclohexanesulfamic acid, sodium salt
Cyclohexanesulphamic acid, monosodium salt
Cyclohexylsulfamic acid, sodium salt
Cyclohexylsulphamate sodium
Cyclohexylsulphamic acid, monosodium salt
EINECS 205-348-9
Monosodium cyclohexylsulfamate
Natrium cyclamicum
NSC 42195
Sodium cyclohexanesulphamate
Sodium cyclohexyl amidosulphate
Sodium cyclohexyl sulfamate
Sodium cyclohexyl sulphamate
Sodium N-cyclohexylsulfamate
Sodium cyclohexylsulphamidate
Chemical Function
Deodorizer
Flavouring and nutrient
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
pharmaceutical
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
SODIUM CYCLAMATE
ChEMBL ID
CHEMBL273977
Max Phase
2
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Sodium cyclamate
ADI
7 mg/kg bw
Food Category
sweetener
Frequently Asked Questions
Is Sodium Cyclamate allowed in the EU?
Sodium Cyclamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Cyclamate do in cosmetics?
Sodium Cyclamate functions as: Artificial sweetener — not a standard cosmetic functional ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 139-05-9.
Is Sodium Cyclamate used outside cosmetics?
Sodium Cyclamate also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Cyclamate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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