Also known as: Phosphonic acid, [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis-, sodium salt, Phosphonic acid, [[bis[2-[bis(phosphonomethyl)amino]ethyl]amino]methyl]-, sodium salt, Briquest 221, Briquest 543-25S, Briquest 543-45 (+15 more)
INCI: SODIUM DIETHYLENETRIAMINE PENTAMETHYLENE PHOSPHONATE
Sodium Diethylenetriamine Pentamethylene Phosphonate (CAS 22042-96-2) is a cosmetic cosmetic ingredient functioning as Chelating Agent. Reported NOAEL =82.5 mg/kg bw/day in Rat (ECHA); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 22042-96-2 →
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Diethylenetriamine Pentamethylene Phosphonate.
Calculate MoS for your specific formulation with the MoS Calculator.
3 study endpoints found for Sodium Diethylenetriamine Pentamethylene Phosphonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =82.5 mg/kg bw/day | oral | Rat | subchronic | ECHA |
| NOAEL | =92.3 mg/kg bw/day | oral | Rat | subchronic | ECHA |
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ECHA |
Preliminary editorial summary for Sodium Diethylenetriamine Pentamethylene Phosphonate — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to Sodium Diethylenetriamine Pentamethylene Phosphonate by CAS number or substance name.
Sodium Diethylenetriamine Pentamethylene Phosphonate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 3 toxicological study endpoint(s) are available in our database.
Sodium Diethylenetriamine Pentamethylene Phosphonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Sodium Diethylenetriamine Pentamethylene Phosphonate functions as: Chelating Agent. It is classified as a cosmetic ingredient in our database. CAS number: 22042-96-2.
The NOAEL (No Observed Adverse Effect Level) for Sodium Diethylenetriamine Pentamethylene Phosphonate is =82.5 mg/kg bw/day based on a subchronic study via oral route in Rat. A total of 3 study endpoints are available. Source: ECHA.
Check Sodium Diethylenetriamine Pentamethylene Phosphonate compliance across multiple jurisdictions:
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Diethylenetriamine Pentamethylene Phosphonate in your formulation.