Sodium Lauroyl Glutamate

INCI: SODIUM LAUROYL GLUTAMATE

Sodium Lauroyl Glutamate (CAS 29923-31-7) is a cosmetic cosmetic ingredient functioning as Surfactant (cleansing/foaming), hair conditioning, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 29923-31-7 →

Auto-generated CPSR Part A draft with source citations
Function
Surfactant (cleansing/foaming), hair conditioning, skin conditioning
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
C17H30NNaO5
MW
351.4 g/mol
EC Number
249-958-3
PubChem CID
23668603
IUPAC Name
sodium (2S)-2-(dodecanoylamino)-5-hydroxy-5-oxopentanoate
InChIKey
IWIUXJGIDSGWDN-UQKRIMTDSA-M

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes EPA Safer Choice Green Circle verified low concern; no FDA monograph restrictions.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Lauroyl Glutamate.

Calculate MoS for your specific formulation with the MoS Calculator.

EPA ToxValDB — Toxicity Values

1 toxicity value from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 =5500 mg/kg Mouse oral - ChemIDplus

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

9 property records from structured ingredient metadata.

acne
{"cas_number": "29923-31-7", "anti_acne_mechanism": "antibacterial", "comedogenicity_rating_0_to_5": "0-1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_a…
amino_acid
{"cas_number": "29923-31-7", "ingredient_class": "amino_acid", "source_origin": "synthetic", "molecular_weight_range_Da": "321", "amino_acid_composition_key": "lauroyl_glutamic_acid", "charge_at_pH_5_5": "anionic", "water_solubility": "soluble", "oil_solubility": "partially", "film_forming_ability": "moderate", "moisture_binding_capacity": "good", "NMF_component": "no", "skin_penetration_depth": "…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,oily,sensitive,combination,normal,acne-prone", "acne_safe": "yes", "source": "Very gentle"}
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "28-60", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low aquatic toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "pa…
emulsifier
{"cas_number": "29923-31-7", "ingredient_class": "O/W_emulsifier,PEG_free_emulsifier", "chemical_type": "amino_acid_based", "HLB_value": "15.0", "HLB_required_for_oil_phase": "13-17", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "0.5-2", "critical_micelle_concentration_pct": "0.01-0.05", "surface_tension_reduction_mN_m": "35", "interfacial_tension_reduction": "39", "foam_formation": …
microbiome_impact
{"microbiome_effect": "neutral", "prebiotic": "yes", "probiotic_compatible": "yes", "preservative_effect_on_microbiome": "Amino acid surfactant; skin-identical; supports microbiome", "gut_microbiome_risk": "low", "microbiome_recovery_time": "<3 days", "selective_antimicrobial": "no", "beneficial_bacteria_support": "S. epidermidis, Lactobacillus spp, Corynebacterium spp", "fermentation_derived": "y…
ph_stability
{"optimal_ph_min": "5.5", "optimal_ph_max": "7.5", "stable_ph_min": "5.0", "stable_ph_max": "8.0", "degrades_above_ph": "9.0", "degrades_below_ph": "4.5", "ph_dependent_function": "Amino acid surfactant", "formulation_note": "Excellent mildness", "source": "Formulation literature"}
sensory
{"silky": "light", "smooth, glides easily": "smooth, mild foam", "dry-touch, non-greasy": "clean, soft", "instant": "fast", "none": "medium", "low": "low", "w/o": "o/w", "very-high": "high", "no": "no", "yes": "no", "1.40": "1.48", "transparent": "transparent", "colorless": "pale-yellow", "excellent": "excellent", "light": "light", "synthetic": "botanical"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Softener and conditioner Surfactant (surface active agent)
Regulatory List Membership (2)
EU Restricted for Children (Cosmetics) EPA Safer Chemical Ingredients List (SCIL)

Expert Verdict

Expert safety assessment and concern-level summary for Sodium Lauroyl Glutamate.

Regulatory Flags

eu_children_restricted epa_safer_alternative

Chemical Function

Surfactant (surface active agent) Softener and conditioner Anti-static agent

Regulatory Lists

children; Europe; Personal care children; Europe; Personal care - hair styling and care - shampoo SCIL (9/2019)

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Sodium Lauroyl Glutamate safe in cosmetics?

Sodium Lauroyl Glutamate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Sodium Lauroyl Glutamate allowed in the EU?

Sodium Lauroyl Glutamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Lauroyl Glutamate do in cosmetics?

Sodium Lauroyl Glutamate functions as: Surfactant (cleansing/foaming), hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 29923-31-7.

Is Sodium Lauroyl Glutamate used outside cosmetics?

Sodium Lauroyl Glutamate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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