Is Sodium Metaphosphate safe in cosmetics?
Sodium Metaphosphate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.
Sodium Metaphosphate
Also known as: SODIUM PHOSPHATE, Metafos, Sodium metaphosphate (Na(PO3)), Sodium phosphate (NaPO3), METAPHOSPHORIC ACID, SODIUM SALT (+2 more)
INCI: SODIUM METAPHOSPHATE
Sodium Metaphosphate (CAS 10361-03-2) is a cosmetic cosmetic ingredient functioning as Buffering, Chelating, Oral Care. Reported NOAEL =100 mg/kg bw/day in Dog (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 10361-03-2 →
Auto-generated CPSR Part A draft with source citations
Function
Buffering, Chelating, Oral Care
Safety Rating
GOOD
Chemistry & Identifiers
InChIKey
AQMNWCRSESPIJM-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use; also GRAS for food applications
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Metaphosphate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Sodium Metaphosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =100 mg/kg bw/day | oral | Dog | short-term | ToxValDB_ECHA_IUCLID |
| NOAEL | =1000 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
mineral_clay
{"cas_number": "10361-03-2", "ingredient_class": "other", "chemical_formula": "(NaPO3)n", "mineral_origin": "synthetic", "particle_size_range_um": "5-50", "surface_area_m2_per_g": "2-15", "crystal_structure": "amorphous", "color_appearance": "white", "opacity": "opaque", "refractive_index": "1.52", "oil_absorption_g_per_100g": "40-100", "water_absorption_capacity": "low", "surface_charge_at_pH_7":…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chelating agent
Emulsifier
Flavouring and nutrient
Surfactant (surface active agent)
Thickening agent
pH regulating agent
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Metaphosphate.
Regulatory Flags
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Sodium Metaphosphate by CAS number or substance name.
Studies
2
Lowest NOAEL
100 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
SODIUM PHOSPHATE
Metafos
Sodium metaphosphate (Na(PO3))
Sodium phosphate (NaPO3)
METAPHOSPHORIC ACID, SODIUM SALT
EINECS 233-782-9
Metaphosphoric acid (HPO3), sodium salt, homopolymer
Chemical Function
Chelating agent
pH regulating agent
Flavouring and nutrient
Thickening agent
Emulsifier
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
active_ingredient; Europe; Pesticides
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Sodium Metaphosphate allowed in the EU?
Sodium Metaphosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Metaphosphate do in cosmetics?
Sodium Metaphosphate functions as: Buffering, Chelating, Oral Care. It is classified as a cosmetic ingredient in our database. CAS number: 10361-03-2.
What is the NOAEL for Sodium Metaphosphate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Metaphosphate is =100 mg/kg bw/day based on a short-term study via oral route in Dog. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is Sodium Metaphosphate used outside cosmetics?
Sodium Metaphosphate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Metaphosphate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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