Is Sodium Pyruvate safe in cosmetics?
Sodium Pyruvate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Sodium Pyruvate
Also known as: EINECS 204-024-4, UNII-POD38AIF08, Natrum pyruvicum
INCI: SODIUM PYRUVATE
Sodium Pyruvate (CAS 113-24-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 113-24-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
sodium 2-oxopropanoate
InChIKey
DAEPDZWVDSPTHF-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Not specifically regulated as a drug; permitted in cosmetics under FDA general cosmetic provisions (no monograph)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Pyruvate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Sodium Pyruvate.
Regulatory Flags
potential-allergen
Known Synonyms
EINECS 204-024-4
UNII-POD38AIF08
Natrum pyruvicum
Chemical Function
Softener and conditioner
Regulatory Lists
pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PYRUVATE SODIUM
ChEMBL ID
CHEMBL181886
Max Phase
2
Frequently Asked Questions
Is Sodium Pyruvate allowed in the EU?
Sodium Pyruvate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Pyruvate do in cosmetics?
Sodium Pyruvate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 113-24-6.
Is Sodium Pyruvate used outside cosmetics?
Sodium Pyruvate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sodium Pyruvate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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SODIUM (ASTROCARYUM VULGARE/EUTERPE OLERACEAE/PALM) FRUIT/(ASTROCARYUM VULGARE/PALM) KERNEL/(ASTROCARYUM MURUMURU/BABASSU/BERTHOLLETIA EXCELSA/CARAPA GUIANENSIS/COCOA/FEVILLEA TRILOBATA/PASSIFLORA EDULIS/THEOBROMA GRANDIFLORUM) SEEDATE
Good
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Cleansing, Surfactant - Cleansing
SODIUM BEHENOYL/COCOYL (ALANINE/ARGININE/ASPARAGINE/ASPARTIC ACID/GLUTAMIC ACID/GLYCINE/ISOLEUCINE/LEUCINE/LYSINE/METHIONINE/PHENYLALANINE/PROLINE/SERINE/THREONINE/TRYPTOPHAN/TYROSINE/VALINE)
Good
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