Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Sodium Pyruvate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 0.0339 mg/L air | 1992 | rat | inhalation | REACH |
| NOEL | 367.4 mg/kg bw/day | oral | code:3544 | oral | REACH |
| NOEL | 188.75 mg/kg bw/day | oral | code:3544 | oral | REACH |
Expert Verdict
CLP-classified skin sensitizer (H317); eye irritant Cat. 2 (H319). Requires careful concentration management and IFRA-style exposure limits in leave-on formulations
Regulatory Flags
Frequently Asked Questions
Is Sodium Pyruvate safe in cosmetics?
CLP-classified skin sensitizer (H317); eye irritant Cat. 2 (H319). Requires careful concentration management and IFRA-style exposure limits in leave-on formulations The EU classifies Sodium Pyruvate as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Sodium Pyruvate allowed in the EU?
Sodium Pyruvate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Pyruvate do in cosmetics?
Sodium Pyruvate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 113-24-6.
What is the Margin of Safety for Sodium Pyruvate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Pyruvate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Pyruvate is 0.0339 mg/L air based on a inhalation study via 1992 route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
Check Sodium Pyruvate compliance across multiple jurisdictions:
Related Ingredients
Is Sodium Pyruvate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Pyruvate in your formulation.