Spleen Hydrolysate

INCI: SPLEEN HYDROLYSATE

CAS Number
91082-29-2
Function
Skin conditioning, humectant (hydrolyzed protein fraction)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted but subject to BSE sourcing restrictions for ruminant materials

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐Ÿšซ Same TSE/BSE prion risk as spleen extract. Additional concern: hydrolyzed animal proteins have documented history of causing protein contact dermatitis and Type I hypersensitivity (reference: Gluten-free wheat hydrolysate class action, Japan 2011). Not COSMOS/ECOCERT eligible. Consider plant-derived peptide alternatives.

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Spleen Hydrolysate safe in cosmetics?

๐Ÿšซ Same TSE/BSE prion risk as spleen extract. Additional concern: hydrolyzed animal proteins have documented history of causing protein contact dermatitis and Type I hypersensitivity (reference: Gluten-free wheat hydrolysate class action, Japan 2011). Not COSMOS/ECOCERT eligible. Consider plant-derived peptide alternatives. The EU classifies Spleen Hydrolysate as "permitted". Safety rating: MODERATE.

Is Spleen Hydrolysate allowed in the EU?

Spleen Hydrolysate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Spleen Hydrolysate do in cosmetics?

Spleen Hydrolysate functions as: Skin conditioning, humectant (hydrolyzed protein fraction). It is classified as a cosmetic ingredient in our database. CAS number: 91082-29-2.

What is the Margin of Safety for Spleen Hydrolysate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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