Spleen Extract

INCI: SPLEEN EXTRACT

CAS Number
91082-28-1
Function
Skin conditioning (historically used in anti-aging/regenerative claims)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted but subject to BSE guidance for ruminant-derived materials

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐Ÿšซ TSE/BSE prion risk if sourced from ruminant species. Must have documented species origin, country of origin (BSE-free), and tissue processing validation. Increasingly avoided in modern cosmetics due to ethical/regulatory burden. Not COSMOS/ECOCERT eligible.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Spleen Extract safe in cosmetics?

๐Ÿšซ TSE/BSE prion risk if sourced from ruminant species. Must have documented species origin, country of origin (BSE-free), and tissue processing validation. Increasingly avoided in modern cosmetics due to ethical/regulatory burden. Not COSMOS/ECOCERT eligible. The EU classifies Spleen Extract as "permitted". Safety rating: MODERATE.

Is Spleen Extract allowed in the EU?

Spleen Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Spleen Extract do in cosmetics?

Spleen Extract functions as: Skin conditioning (historically used in anti-aging/regenerative claims). It is classified as a cosmetic ingredient in our database. CAS number: 91082-28-1.

What is the Margin of Safety for Spleen Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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