Sucrose Octaacetate

INCI: SUCROSE OCTAACETATE

CAS Number
126-14-7
Function
Denaturant, Fragrance ingredient
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted as cosmetic ingredient and direct food additive (21CFR172.515); NOT GRAS for OTC nail-biting/thumb-sucking deterrent drug use (21CFR310.536)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

FDA explicitly states NOT GRAS as OTC drug for nail-biting deterrence (21CFR310.536) โ€” safety data insufficient for drug-level exposure. Extremely bitter taste (used as denaturant/aversive agent). No current VCRP cosmetic uses. Melting point 89โ€“93ยฐC. Hygroscopic.

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Concern Level: Low

Regulatory Flags

fragrance-component fda_food_additive

Frequently Asked Questions

Is Sucrose Octaacetate safe in cosmetics?

FDA explicitly states NOT GRAS as OTC drug for nail-biting deterrence (21CFR310.536) โ€” safety data insufficient for drug-level exposure. Extremely bitter taste (used as denaturant/aversive agent). No current VCRP cosmetic uses. Melting point 89โ€“93ยฐC. Hygroscopic. The EU classifies Sucrose Octaacetate as "permitted". Safety rating: GOOD.

Is Sucrose Octaacetate allowed in the EU?

Sucrose Octaacetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sucrose Octaacetate do in cosmetics?

Sucrose Octaacetate functions as: Denaturant, Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 126-14-7.

What is the Margin of Safety for Sucrose Octaacetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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