Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Synthetic Wax. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 17 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 17 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1815 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1815 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 160 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 157 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 1000 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Safe when properly refined to remove PAHs. EU and GMP compliance requires full refining documentation and PAH content below detectable thresholds. Dermal penetration negligible.
Regulatory Flags
Frequently Asked Questions
Is Synthetic Wax safe in cosmetics?
Safe when properly refined to remove PAHs. EU and GMP compliance requires full refining documentation and PAH content below detectable thresholds. Dermal penetration negligible. The EU classifies Synthetic Wax as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Synthetic Wax allowed in the EU?
Synthetic Wax EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Synthetic Wax do in cosmetics?
Synthetic Wax functions as: Binding, Emulsion Stabilizing, Viscosity Controlling. It is classified as a Emollient in our database. CAS number: 8002-74-2.
What is the Margin of Safety for Synthetic Wax?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Synthetic Wax?
The NOAEL (No Observed Adverse Effect Level) for Synthetic Wax is 1000 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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