Tafluprost

INCI: ETHYL TAFLUPROSTAMIDE (COSMETIC INCI); INN: TAFLUPROST

CAS Number
209860-87-7
Function
Prostaglandin F2α analogue – used in eyelash growth/conditioning products
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes FDA-approved as ophthalmic drug (glaucoma treatment); cosmetic use in eyelash serums occupies a regulatory grey area

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

🔴 CRITICAL: Pharmaceutical active ingredient. Iris color change (irreversible). Periorbital fat loss. EU actively investigating prostaglandins in cosmetics for potential prohibition. Do NOT formulate without full regulatory clearance

⚠️
Concern Level: High

Frequently Asked Questions

Is Tafluprost safe in cosmetics?

🔴 CRITICAL: Pharmaceutical active ingredient. Iris color change (irreversible). Periorbital fat loss. EU actively investigating prostaglandins in cosmetics for potential prohibition. Do NOT formulate without full regulatory clearance The EU classifies Tafluprost as "permitted". Safety rating: POOR.

Is Tafluprost allowed in the EU?

Tafluprost EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tafluprost do in cosmetics?

Tafluprost functions as: Prostaglandin F2α analogue – used in eyelash growth/conditioning products. It is classified as a cosmetic ingredient in our database. CAS number: 209860-87-7.

What is the Margin of Safety for Tafluprost?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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