Tapirira guianensis Leaf Extract

INCI: TAPIRIRA GUIANENSIS LEAF EXTRACT

CAS Number
Not formally assigned for cosmetic use
Function
Skin conditioning; stimulates expression of perlecan, dystroglycan, VE-cadherin, and claudin-5 in dermoepidermal junction
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; permitted as a botanical cosmetic ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited safety data. Seed extracts have shown antiproliferative activity , so biological potency should be considered. Relatively novel cosmetic ingredient โ€” a full safety dossier including dermal irritation, sensitization, and genotoxicity testing is recommended before commercial use.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Tapirira guianensis Leaf Extract safe in cosmetics?

Limited safety data. Seed extracts have shown antiproliferative activity , so biological potency should be considered. Relatively novel cosmetic ingredient โ€” a full safety dossier including dermal irritation, sensitization, and genotoxicity testing is recommended before commercial use. The EU classifies Tapirira guianensis Leaf Extract as "permitted". Safety rating: MODERATE.

Is Tapirira guianensis Leaf Extract allowed in the EU?

Tapirira guianensis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tapirira guianensis Leaf Extract do in cosmetics?

Tapirira guianensis Leaf Extract functions as: Skin conditioning; stimulates expression of perlecan, dystroglycan, VE-cadherin, and claudin-5 in dermoepidermal junction. It is classified as a cosmetic ingredient in our database. CAS number: Not formally assigned for cosmetic use.

What is the Margin of Safety for Tapirira guianensis Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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