Excellent Cosmetic Ingredient NOAEL Data

TEA-Cocoyl Glutamate

INCI: TEA-COCOYL GLUTAMATE

CAS Number
68187-29-1
Function
Surfactant – Cleansing, Hair Conditioning
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted; CIR: safe in present practices of use (amino acid alkyl amides group)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for TEA-Cocoyl Glutamate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 1080 mg/kg bw/day oral rat oral REACH
NOEL 1080 mg/kg bw/day oral rat oral REACH

Expert Verdict

Nitrosamine formation risk from TEA component; plant-derived (coconut oil + fermented L-glutamic acid); no nitrosating systems

⚠️
Concern Level: None

Regulatory Flags

natural-origin

Frequently Asked Questions

Is TEA-Cocoyl Glutamate safe in cosmetics?

Nitrosamine formation risk from TEA component; plant-derived (coconut oil + fermented L-glutamic acid); no nitrosating systems The EU classifies TEA-Cocoyl Glutamate as "restricted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.

Is TEA-Cocoyl Glutamate allowed in the EU?

TEA-Cocoyl Glutamate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does TEA-Cocoyl Glutamate do in cosmetics?

TEA-Cocoyl Glutamate functions as: Surfactant – Cleansing, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68187-29-1.

What is the Margin of Safety for TEA-Cocoyl Glutamate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for TEA-Cocoyl Glutamate?

The NOAEL (No Observed Adverse Effect Level) for TEA-Cocoyl Glutamate is 1080 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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