Is Telmesteine safe in cosmetics?
Telmesteine has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Telmesteine
Also known as: Telmesteina, Telmesteinum, UNII-124I3FE35T
INCI: TELMESTEINE
Telmesteine (CAS 122946-43-4) is a cosmetic cosmetic ingredient functioning as Skin conditioning; originally a mucolytic/anti-inflammatory pharmaceutical agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 122946-43-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning; originally a mucolytic/anti-inflammatory pharmaceutical agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
InChIKey
XBJWOGLKABXFJE-YFKPBYRVSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not FDA-approved as a drug in the US; permitted in cosmetics under general provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Telmesteine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Expert Verdict
Expert safety assessment and concern-level summary for Telmesteine.
Known Synonyms
Telmesteina
Telmesteinum
UNII-124I3FE35T
Chemical Function
Antioxidant
Regulatory Lists
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
TELMESTEINE
ChEMBL ID
CHEMBL2107621
Max Phase
2
Frequently Asked Questions
Is Telmesteine allowed in the EU?
Telmesteine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Telmesteine do in cosmetics?
Telmesteine functions as: Skin conditioning; originally a mucolytic/anti-inflammatory pharmaceutical agent. It is classified as a cosmetic ingredient in our database. CAS number: 122946-43-4.
Is Telmesteine used outside cosmetics?
Telmesteine also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Telmesteine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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