Moderate Cosmetic Ingredient NOAEL Data

Terpene Hydrocarbons

INCI: TERPENE HYDROCARBONS (ALSO: HYDROCARBONS, TERPENE PROCESSING BY-PRODUCTS)

CAS Number
68956-56-9
Function
Fragrance, solvent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted as fragrance ingredient

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

5 study endpoints found for Terpene Hydrocarbons. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 50 ppm 1991 mouse inhalation REACH
NOAEL 435.8 mg/kg bw/day oral rat oral REACH
NOEL 250 mg/kg bw/day oral rat oral REACH
LOAEL 25 ppm 1991 rat inhalation REACH
NOAEL 1500 ppm oral rat oral REACH

Expert Verdict

GHS classification: H316, H317, H320 . UVCB substance — variable composition means batch-to-batch consistency must be verified. Contains components (limonene, alpha-pinene, camphene) subject to EU allergen declaration. May contain 1,8-cineole . Auto-oxidation generates sensitizers

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance eu_cosing_listed

Frequently Asked Questions

Is Terpene Hydrocarbons safe in cosmetics?

GHS classification: H316, H317, H320 . UVCB substance — variable composition means batch-to-batch consistency must be verified. Contains components (limonene, alpha-pinene, camphene) subject to EU allergen declaration. May contain 1,8-cineole . Auto-oxidation generates sensitizers The EU classifies Terpene Hydrocarbons as "restricted". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.

Is Terpene Hydrocarbons allowed in the EU?

Terpene Hydrocarbons EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Terpene Hydrocarbons do in cosmetics?

Terpene Hydrocarbons functions as: Fragrance, solvent. It is classified as a cosmetic ingredient in our database. CAS number: 68956-56-9.

What is the Margin of Safety for Terpene Hydrocarbons?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Terpene Hydrocarbons?

The NOAEL (No Observed Adverse Effect Level) for Terpene Hydrocarbons is 50 ppm based on a inhalation study via 1991 route in mouse. A total of 5 study endpoints are available. Source: REACH.

Compliance Tools

Check Terpene Hydrocarbons compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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