Tetrahexadecyl Ascorbate

INCI: TETRAHEXADECYL ASCORBATE

Function
Antioxidant, Skin Conditioning
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted. CIR reviewed (2017) as part of ethers/esters of ascorbic acid โ€” safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Non-comedogenic lipophilic vitamin C ester with excellent safety profile; safe up to approximately 30% in most markets, but Australian AICS limits to 1% for cosmetic dermal use โ€” verify concentration limits for target market.

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Concern Level: Low

Frequently Asked Questions

Is Tetrahexadecyl Ascorbate safe in cosmetics?

Non-comedogenic lipophilic vitamin C ester with excellent safety profile; safe up to approximately 30% in most markets, but Australian AICS limits to 1% for cosmetic dermal use โ€” verify concentration limits for target market. The EU classifies Tetrahexadecyl Ascorbate as "permitted". Safety rating: EXCELLENT.

Is Tetrahexadecyl Ascorbate allowed in the EU?

Tetrahexadecyl Ascorbate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tetrahexadecyl Ascorbate do in cosmetics?

Tetrahexadecyl Ascorbate functions as: Antioxidant, Skin Conditioning. It is classified as a cosmetic ingredient in our database.

What is the Margin of Safety for Tetrahexadecyl Ascorbate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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