Tetramethylhexanal

INCI: TETRAMETHYLHEXANAL

CAS Number
Likely 5765-44-6 (2,2,4,4-tetramethylhexanal) or positional isomer — verify exact substitution pattern
Function
Fragrance ingredient — aldehyde with fresh/green character
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted under general fragrance provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Aliphatic aldehyde sensitization mechanism (Schiff base formation); auto-oxidation during storage increases sensitization risk. IFRA use limits likely apply

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Tetramethylhexanal safe in cosmetics?

Aliphatic aldehyde sensitization mechanism (Schiff base formation); auto-oxidation during storage increases sensitization risk. IFRA use limits likely apply The EU classifies Tetramethylhexanal as "permitted". Safety rating: MODERATE.

Is Tetramethylhexanal allowed in the EU?

Tetramethylhexanal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tetramethylhexanal do in cosmetics?

Tetramethylhexanal functions as: Fragrance ingredient — aldehyde with fresh/green character. It is classified as a cosmetic ingredient in our database. CAS number: Likely 5765-44-6 (2,2,4,4-tetramethylhexanal) or positional isomer — verify exact substitution pattern.

What is the Margin of Safety for Tetramethylhexanal?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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