Theobroma Cacao Leaf Cell Extract
INCI: THEOBROMA CACAO LEAF CELL EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Theobroma Cacao Leaf Cell Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 4280 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 2140 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Classified as fragrance — must declare 26 EU allergens if present above threshold; limited standalone toxicological data
Regulatory Flags
Frequently Asked Questions
Is Theobroma Cacao Leaf Cell Extract safe in cosmetics?
Classified as fragrance — must declare 26 EU allergens if present above threshold; limited standalone toxicological data The EU classifies Theobroma Cacao Leaf Cell Extract as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Theobroma Cacao Leaf Cell Extract allowed in the EU?
Theobroma Cacao Leaf Cell Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Theobroma Cacao Leaf Cell Extract do in cosmetics?
Theobroma Cacao Leaf Cell Extract functions as: Fragrance, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 84649-99-0.
What is the Margin of Safety for Theobroma Cacao Leaf Cell Extract?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Theobroma Cacao Leaf Cell Extract?
The NOAEL (No Observed Adverse Effect Level) for Theobroma Cacao Leaf Cell Extract is 4280 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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