Is Thioxanthone safe in cosmetics?
Thioxanthone has a safety rating of "POOR" in our database. EU status: permitted. US status: permitted.
Poor
Cosmetic Ingredient
Thioxanthone
Also known as: 9H-Thioxanthen-9-one, EINECS 207-749-4, NSC 15912, Thiaxanthenone, Thiaxanthon (+9 more)
INCI: THIOXANTHONE (NOT AN ASSIGNED COSMETIC INCI — USED AS A PHOTOINITIATOR IN UV-CURING SYSTEMS)
Thioxanthone (CAS 492-22-8) is a cosmetic cosmetic ingredient functioning as Photoinitiator / UV absorber (industrial, not cosmetic). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 492-22-8 →
Auto-generated CPSR Part A draft with source citations
Function
Photoinitiator / UV absorber (industrial, not cosmetic)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
thioxanthen-9-one
InChIKey
YRHRIQCWCFGUEQ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not listed in FDA's Voluntary Cosmetic Registration Program (VCRP) as a cosmetic ingredient; no specific FDA cosmetic monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Thioxanthone.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for Thioxanthone.
Known Synonyms
9H-Thioxanthen-9-one
EINECS 207-749-4
NSC 15912
Thiaxanthenone
Thiaxanthon
Thiaxanthone
Thioxanthene, 9-oxo-
9H-Thioxanthene, 9-oxo-
Thioxanthene-9-one
Thioxanthenone
10-Thioxanthone
9-Thioxanthone
NSC 658181
UNII-EOK1SAC304
Chemical Function
No specific technical function
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL83371
Frequently Asked Questions
Is Thioxanthone allowed in the EU?
Thioxanthone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Thioxanthone do in cosmetics?
Thioxanthone functions as: Photoinitiator / UV absorber (industrial, not cosmetic). It is classified as a cosmetic ingredient in our database. CAS number: 492-22-8.
Is Thioxanthone used outside cosmetics?
Thioxanthone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Thioxanthone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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THIMEROSAL
Moderate
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Preservative
THYMUS LINEARIS LEAF/(ANGELICA GLAUCA/BERGENIA CILIATA) ROOT/PRINSEPIA UTILIS SEED EXTRACT
Good
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Skin Conditioning
THYMUS SERPYLLUM EXTRACT
Good
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Skin Conditioning
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