Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Thymidine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
GHS Warning: skin/eye irritant and respiratory irritant in concentrated pure form (H315, H319, H335); risk statements R20/21/22, R40 (limited evidence of carcinogenic effect in pure lab contexts — not relevant at cosmetic use levels)
Frequently Asked Questions
Is Thymidine safe in cosmetics?
GHS Warning: skin/eye irritant and respiratory irritant in concentrated pure form (H315, H319, H335); risk statements R20/21/22, R40 (limited evidence of carcinogenic effect in pure lab contexts — not relevant at cosmetic use levels) The EU classifies Thymidine as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Thymidine allowed in the EU?
Thymidine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Thymidine do in cosmetics?
Thymidine functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 50-89-5.
What is the Margin of Safety for Thymidine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Thymidine?
The NOAEL (No Observed Adverse Effect Level) for Thymidine is 1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
Check Thymidine compliance across multiple jurisdictions:
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