Tiarella Polyphylla Extract

INCI: TIARELLA POLYPHYLLA EXTRACT

CAS Number
Not assigned (no CAS in CosIng database)
Function
Skin conditioning, anti-aging (anti-photoaging) — shown to induce procollagen type I and regulate MMP-1 expression in UV-damaged fibroblasts
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted for cosmetic use; not specifically regulated; manufacturer bears burden of safety proof

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Very limited safety data; no comprehensive toxicological dossier (no NOAEL, no repeat-dose dermal studies); primarily supported by in vitro studies; endemic to Ulleung Island (Korea) — supply chain traceability critical; novel ingredient that would need robust safety substantiation for EU CPSR

⚠️
Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Tiarella Polyphylla Extract safe in cosmetics?

Very limited safety data; no comprehensive toxicological dossier (no NOAEL, no repeat-dose dermal studies); primarily supported by in vitro studies; endemic to Ulleung Island (Korea) — supply chain traceability critical; novel ingredient that would need robust safety substantiation for EU CPSR The EU classifies Tiarella Polyphylla Extract as "permitted". Safety rating: GOOD.

Is Tiarella Polyphylla Extract allowed in the EU?

Tiarella Polyphylla Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tiarella Polyphylla Extract do in cosmetics?

Tiarella Polyphylla Extract functions as: Skin conditioning, anti-aging (anti-photoaging) — shown to induce procollagen type I and regulate MMP-1 expression in UV-damaged fibroblasts. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (no CAS in CosIng database).

What is the Margin of Safety for Tiarella Polyphylla Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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