Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Tin (Sn). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | >1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >1000 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Must be distinguished from organotin compounds (dibutyltin, tributyltin) which are Annex II prohibited ; heavy metal contamination limits apply; ensure speciation testing
Frequently Asked Questions
Is Tin (Sn) safe in cosmetics?
Must be distinguished from organotin compounds (dibutyltin, tributyltin) which are Annex II prohibited ; heavy metal contamination limits apply; ensure speciation testing The EU classifies Tin (Sn) as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Tin (Sn) allowed in the EU?
Tin (Sn) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Tin (Sn) do in cosmetics?
Tin (Sn) functions as: Bulking agent, opacifying agent (limited cosmetic use). It is classified as a cosmetic ingredient in our database. CAS number: 7440-31-5.
What is the Margin of Safety for Tin (Sn)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Tin (Sn)?
The NOAEL (No Observed Adverse Effect Level) for Tin (Sn) is >1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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