Is Toluene Diisocyanate safe in cosmetics?
Toluene Diisocyanate has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
POOR
Cosmetic Ingredient
Toluene Diisocyanate
INCI: TOLUENE DIISOCYANATE
Toluene Diisocyanate (CAS 584-84-9 (2,4-TDI); 91-08-7 (2,6-TDI); 26471-62-5 (mixed isomers)) is a cosmetic cosmetic ingredient functioning as Not a cosmetic ingredient; industrial polyurethane precursor. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
CAS Number
584-84-9 (2,4-TDI); 91-08-7 (2,6-TDI); 26471-62-5 (mixed isomers)
View industrial chemical safety profile →
Function
Not a cosmetic ingredient; industrial polyurethane precursor
Editorial assessment
POOR
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Listed on the Cosmetic Ingredient Hotlist (prohibited)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Toluene Diisocyanate.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Toluene Diisocyanate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
prop65
eu_banned_cosmetics
eu_cosing_listed
Frequently Asked Questions
Is Toluene Diisocyanate allowed in the EU?
Toluene Diisocyanate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Toluene Diisocyanate do in cosmetics?
Toluene Diisocyanate functions as: Not a cosmetic ingredient; industrial polyurethane precursor. It is classified as a cosmetic ingredient in our database. CAS number: 584-84-9 (2,4-TDI); 91-08-7 (2,6-TDI); 26471-62-5 (mixed isomers).
Compliance Tools
Check Toluene Diisocyanate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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