Is Trans-2-Decenal safe in cosmetics?
Trans-2-Decenal has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
MODERATE
Cosmetic Ingredient
Trans-2-Decenal
Also known as: 2-Decen-1-al, Decenaldehyde, Decylenic aldehyde, EINECS 223-472-1, NSC 20747 (+4 more)
INCI: TRANS-2-DECENAL
Trans-2-Decenal (CAS 3913-71-1) is a cosmetic cosmetic ingredient functioning as Fragrance. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
Function
Fragrance
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
(E)-dec-2-enal
InChIKey
MMFCJPPRCYDLLZ-CMDGGOBGSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; RIFM peer-reviewed safety assessment published
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Trans-2-Decenal.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
DPRA Cys %
94.9%
DPRA Lys %
9.7%
KeratinoSens IC50
37.765 µM
LLNA EC3
2.5%
NESIL
625 µg/cm²
LLNA: Moderate (1B)
GHS: 1B
Source: LLNA: Gerberick et al. (2005); DPRA: Urbisch et al. 2015 [DOI:10.1016/j.yrtph.2014.12.008]; KS: Urbisch et al. 2015 [DOI:10.1016/j.yrtph.2014.12.008]
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Editorial summary
Preliminary editorial summary for Trans-2-Decenal — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
2-Decen-1-al
Decenaldehyde
Decylenic aldehyde
EINECS 223-472-1
NSC 20747
2-decenaldehyde
3-heptyl-acrolein
3-heptylacrolein
dec-2-enal
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Europe
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Trans-2-Decenal allowed in the EU?
Trans-2-Decenal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trans-2-Decenal do in cosmetics?
Trans-2-Decenal functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 3913-71-1.
Is Trans-2-Decenal used outside cosmetics?
Trans-2-Decenal also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Trans-2-Decenal compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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