Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Triacetin. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1650 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 9500 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 8000 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 12200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 10000 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Not reviewed by SCCS; not on California Safe Cosmetics Program reportable list; not on Canada Cosmetic Ingredient Hotlist . Small MW means higher dermal absorption than large esters — factor into CPSR exposure calculations
Regulatory Flags
Frequently Asked Questions
Is Triacetin safe in cosmetics?
Not reviewed by SCCS; not on California Safe Cosmetics Program reportable list; not on Canada Cosmetic Ingredient Hotlist . Small MW means higher dermal absorption than large esters — factor into CPSR exposure calculations The EU classifies Triacetin as "permitted". Safety rating: EXCELLENT. 7 toxicological study endpoint(s) are available in our database.
Is Triacetin allowed in the EU?
Triacetin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Triacetin do in cosmetics?
Triacetin functions as: Plasticizer, solvent, cosmetic biocide (antifungal via acetic acid release), hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 102-76-1.
What is the Margin of Safety for Triacetin?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Triacetin?
The NOAEL (No Observed Adverse Effect Level) for Triacetin is 1650 mg/kg bw/day based on a Chronic study via oral route in rat. A total of 7 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check Triacetin compliance across multiple jurisdictions:
Related Ingredients
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