Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Tributylcresylbutane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 ppm | oral | rat | oral | REACH |
Expert Verdict
Synthetic origin; also known as 1,1,3-Tris(2-methyl-4-hydroxy-5-tert-butylphenyl)butane; primarily in nail polishes — limited systemic exposure; limited publicly available toxicological data
Frequently Asked Questions
Is Tributylcresylbutane safe in cosmetics?
Synthetic origin; also known as 1,1,3-Tris(2-methyl-4-hydroxy-5-tert-butylphenyl)butane; primarily in nail polishes — limited systemic exposure; limited publicly available toxicological data The EU classifies Tributylcresylbutane as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Tributylcresylbutane allowed in the EU?
Tributylcresylbutane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tributylcresylbutane do in cosmetics?
Tributylcresylbutane functions as: Film-forming, plasticizer, solvent. It is classified as a cosmetic ingredient in our database. CAS number: 1843-03-4.
What is the Margin of Safety for Tributylcresylbutane?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Tributylcresylbutane?
The NOAEL (No Observed Adverse Effect Level) for Tributylcresylbutane is 500 ppm based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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