Trichosanthes Kirilowii Seed Extract

INCI: TRICHOSANTHES KIRILOWII SEED EXTRACT

CAS Number
No unique CAS assigned (botanical extract)
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted; general use permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Seeds of *T. kirilowii* contain trichosanthin (a ribosome-inactivating protein); extraction method must ensure adequate removal/denaturation; requires robust toxicological dossier in CPSR

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Trichosanthes Kirilowii Seed Extract safe in cosmetics?

Seeds of *T. kirilowii* contain trichosanthin (a ribosome-inactivating protein); extraction method must ensure adequate removal/denaturation; requires robust toxicological dossier in CPSR The EU classifies Trichosanthes Kirilowii Seed Extract as "permitted". Safety rating: MODERATE.

Is Trichosanthes Kirilowii Seed Extract allowed in the EU?

Trichosanthes Kirilowii Seed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trichosanthes Kirilowii Seed Extract do in cosmetics?

Trichosanthes Kirilowii Seed Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: No unique CAS assigned (botanical extract).

What is the Margin of Safety for Trichosanthes Kirilowii Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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