Good Cosmetic Ingredient NOAEL Data

Tridecane

INCI: TRIDECANE

CAS Number
629-50-5
Function
Skin Conditioning, Emollient, Perfuming, Solvent/carrier
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No substance-specific MoCRA restrictions.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Tridecane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >=1000 mg/kg bw/day oral rat oral REACH
NOAEL >=1000 mg/kg bw/day oral - oral REACH
NOAEL >=1800 2285 1995 rat inhalation REACH
NOAEL >=1800 2285 inhalation - inhalation REACH
NOAEL >=5000 mg/kg bw/day oral rat oral REACH
NOAEL >=5000 mg/kg bw/day oral - oral REACH
NOAEL >=900 ppm 1995 rat inhalation REACH
NOAEL >=900 ppm inhalation - inhalation REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral - oral REACH

Expert Verdict

Low acute toxicity with widespread cosmetic use as COSMOS-certified silicone alternative; irritation data under neat occlusion not representative of formulation use.

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Concern Level: Low

Regulatory Flags

ifra_fragrance

Frequently Asked Questions

Is Tridecane safe in cosmetics?

Low acute toxicity with widespread cosmetic use as COSMOS-certified silicone alternative; irritation data under neat occlusion not representative of formulation use. The EU classifies Tridecane as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Tridecane allowed in the EU?

Tridecane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tridecane do in cosmetics?

Tridecane functions as: Skin Conditioning, Emollient, Perfuming, Solvent/carrier. It is classified as a cosmetic ingredient in our database. CAS number: 629-50-5.

What is the Margin of Safety for Tridecane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Tridecane?

The NOAEL (No Observed Adverse Effect Level) for Tridecane is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

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