Is Cetyl Acetate safe in cosmetics?
Cetyl Acetate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
MODERATE
Cosmetic Ingredient
Cetyl Acetate
Also known as: 4-02-00-00171, BRN 1782695, EINECS 211-103-7, n-Hexadecyl ethanoate, UNII-4Q43814HXS
INCI: CETYL ACETATE
Cetyl Acetate (CAS 629-70-9) is a cosmetic cosmetic ingredient functioning as Fragrance, Skin Conditioning, Skin Conditioning – Emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Function
Fragrance, Skin Conditioning, Skin Conditioning – Emollient
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
hexadecyl acetate
InChIKey
LSTDYDRCKUBPDI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted without restriction; CIR Expert Panel concluded alkyl esters (239 ingredients including Cetyl Acetate) are safe as used when formulated to be non-irritating (2013)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cetyl Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1350 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Fragrance
Softener and conditioner
Regulatory List Membership (3)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Indirect Food Contact Additives
Editorial summary
Preliminary editorial summary for Cetyl Acetate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
epa_safer_alternative
ifra_fragrance
Known Synonyms
4-02-00-00171
BRN 1782695
EINECS 211-103-7
n-Hexadecyl ethanoate
UNII-4Q43814HXS
Chemical Function
Softener and conditioner
Deodorizer
Fragrance
Flavouring and nutrient
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Indirect additives food contact (10/2018)
IFRA Transparency
SCIL (9/2019)
Europe
detected; Europe; Other direct contact consumer goods
detected; Europe; Other direct contact consumer goods
active_ingredient; Europe; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ACETIC ACID HEXADECYL ESTER
ChEMBL ID
CHEMBL137354
Frequently Asked Questions
Is Cetyl Acetate allowed in the EU?
Cetyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cetyl Acetate do in cosmetics?
Cetyl Acetate functions as: Fragrance, Skin Conditioning, Skin Conditioning – Emollient. It is classified as a cosmetic ingredient in our database. CAS number: 629-70-9.
Is Cetyl Acetate used outside cosmetics?
Cetyl Acetate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Cetyl Acetate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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