Regulatory Status
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Safety Data
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Expert Verdict
Dicaprylyl Ether (CAS 629-82-3) is a fatty dialkyl ether emollient permitted without restriction in the EU under Regulation 1223/2009, with industry-reported use levels up to 25% in leave-on products. The CIR Expert Panel concluded it is safe in cosmetics at present practices of use and concentration, supported by a NOAEL โฅ 1000 mg/kg bw/day, very low dermal absorption of 0.3%, and an MoS exceeding 10,000 even in worst-case scenarios. Genotoxicity is negative across Ames, chromosome aberration, and mouse lymphoma assays; the ingredient is non-sensitizing in animal and human tests at cosmetic-relevant concentrations.
Regulatory Flags
Frequently Asked Questions
Is Dicaprylyl Ether safe in cosmetics?
Dicaprylyl Ether (CAS 629-82-3) is a fatty dialkyl ether emollient permitted without restriction in the EU under Regulation 1223/2009, with industry-reported use levels up to 25% in leave-on products. The CIR Expert Panel concluded it is safe in cosmetics at present practices of use and concentration, supported by a NOAEL โฅ 1000 mg/kg bw/day, very low dermal absorption of 0.3%, and an MoS exceeding 10,000 even in worst-case scenarios. Genotoxicity is negative across Ames, chromosome aberration, and mouse lymphoma assays; the ingredient is non-sensitizing in animal and human tests at cosmetic-relevant concentrations. The EU classifies Dicaprylyl Ether as "permitted". Safety rating: EXCELLENT.
Is Dicaprylyl Ether allowed in the EU?
Dicaprylyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dicaprylyl Ether do in cosmetics?
Dicaprylyl Ether functions as: Emollient. It is classified as a Cosmetic Ingredient in our database. CAS number: None.
What is the Margin of Safety for Dicaprylyl Ether?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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