Is Tridecenal (2-Tridecenal) safe in cosmetics?
Tridecenal (2-Tridecenal) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
MODERATE
Cosmetic Ingredient
Tridecenal (2-Tridecenal)
Also known as: NSC 617616, Tridec-2-enal, 3-Decylacrolein, EINECS 231-883-2, FEMA No. 3082
INCI: TRIDECENAL (2-TRIDECENAL)
Tridecenal (2-Tridecenal) (CAS 7774-82-5) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient — fatty, waxy, aldehydic odor profile. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
Function
Fragrance ingredient — fatty, waxy, aldehydic odor profile
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
(E)-tridec-2-enal
InChIKey
VMUNAKQXJLHODT-VAWYXSNFSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted as fragrance ingredient; no specific restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tridecenal (2-Tridecenal).
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
NESIL
2700 µg/cm²
GHS: 1B
Human: positive
Source: HPPT: [751] Epstein WL (1979): Report to RIFM, 9 March and 13 July, unpublished.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
1359
Source: WHO/JECFA
JECFA Evaluation
2-TRIDECENAL | 2004 | No safety concern at current levels of intake when used as a flavouring agent | TRS 928-JECFA 63/77 | FAS 54-JECFA 63/317
Source: WHO/JECFA
JECFA Evaluation
3-DECYLACROLEIN | 2004 | No safety concern at current levels of intake when used as a flavouring agent | TRS 928-JECFA 63/77 | FAS 54-JECFA 63/317
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for Tridecenal (2-Tridecenal) — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
NSC 617616
Tridec-2-enal
3-Decylacrolein
EINECS 231-883-2
FEMA No. 3082
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Tridecenal (2-Tridecenal) allowed in the EU?
Tridecenal (2-Tridecenal) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tridecenal (2-Tridecenal) do in cosmetics?
Tridecenal (2-Tridecenal) functions as: Fragrance ingredient — fatty, waxy, aldehydic odor profile. It is classified as a cosmetic ingredient in our database. CAS number: 7774-82-5.
Is Tridecenal (2-Tridecenal) used outside cosmetics?
Tridecenal (2-Tridecenal) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Tridecenal (2-Tridecenal) compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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