Moderate Cosmetic Ingredient NOAEL Data

Triethylene Glycol Rosinate

INCI: TRIETHYLENE GLYCOL ROSINATE

CAS Number
8050-25-7
Function
Film forming agent, plasticizer, tackifier (viscous rosin ester used in depilatory waxes, adhesives, nail products)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Triethylene Glycol Rosinate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 3000 ppm oral rat oral REACH
NOEL 3000 ppm oral - oral REACH
NOAEL 18000 other oral rat oral REACH
NOEL 500 other oral rat oral REACH
NOEL 500 other oral - oral REACH
NOEL 500 other oral rat oral REACH
NOEL 500 other oral - oral REACH
NOEL 10000 ppm oral rat oral REACH
NOEL 10000 ppm oral - oral REACH
NOAEL 1 other oral rat oral REACH

Expert Verdict

Colophonium/rosin allergy is one of the most common contact allergies (prevalence ~2-4% of patch-tested patients). Non-hydrogenated form carries higher sensitization risk than hydrogenated variant (\#5 above). Oxidation products increase allergenicity. Prefer hydrogenated version when possible

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Triethylene Glycol Rosinate safe in cosmetics?

Colophonium/rosin allergy is one of the most common contact allergies (prevalence ~2-4% of patch-tested patients). Non-hydrogenated form carries higher sensitization risk than hydrogenated variant (\#5 above). Oxidation products increase allergenicity. Prefer hydrogenated version when possible The EU classifies Triethylene Glycol Rosinate as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.

Is Triethylene Glycol Rosinate allowed in the EU?

Triethylene Glycol Rosinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Triethylene Glycol Rosinate do in cosmetics?

Triethylene Glycol Rosinate functions as: Film forming agent, plasticizer, tackifier (viscous rosin ester used in depilatory waxes, adhesives, nail products). It is classified as a cosmetic ingredient in our database. CAS number: 8050-25-7.

What is the Margin of Safety for Triethylene Glycol Rosinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Triethylene Glycol Rosinate?

The NOAEL (No Observed Adverse Effect Level) for Triethylene Glycol Rosinate is 3000 ppm based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

๐Ÿ“ฑ

Is Triethylene Glycol Rosinate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Triethylene Glycol Rosinate in your formulation.