Trimethylbenzene

INCI: TRIMETHYLBENZENE

CAS Number
25551-13-7 (mixed isomers); 95-63-6 (1,2,4-TMB); 108-67-8 (1,3,5-TMB / mesitylene)
Function
Solvent; denaturant; fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not approved as a direct cosmetic ingredient; may appear as residual solvent

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Inhalation toxicity concern; CNS effects; classified as irritant (H304, H335); occupational exposure limits apply; NOT recommended for leave-on cosmetics

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Concern Level: High

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Trimethylbenzene safe in cosmetics?

Inhalation toxicity concern; CNS effects; classified as irritant (H304, H335); occupational exposure limits apply; NOT recommended for leave-on cosmetics The EU classifies Trimethylbenzene as "permitted". Safety rating: MODERATE.

Is Trimethylbenzene allowed in the EU?

Trimethylbenzene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trimethylbenzene do in cosmetics?

Trimethylbenzene functions as: Solvent; denaturant; fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 25551-13-7 (mixed isomers); 95-63-6 (1,2,4-TMB); 108-67-8 (1,3,5-TMB / mesitylene).

What is the Margin of Safety for Trimethylbenzene?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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