Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Trimethylhexanol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 144 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
May cause mild irritation at high concentrations; standard fragrance/solvent use levels are considered safe
Regulatory Flags
Frequently Asked Questions
Is Trimethylhexanol safe in cosmetics?
May cause mild irritation at high concentrations; standard fragrance/solvent use levels are considered safe The EU classifies Trimethylhexanol as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Trimethylhexanol allowed in the EU?
Trimethylhexanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trimethylhexanol do in cosmetics?
Trimethylhexanol functions as: Perfuming / solvent. It is classified as a cosmetic ingredient in our database. CAS number: 3452-97-9.
What is the Margin of Safety for Trimethylhexanol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Trimethylhexanol?
The NOAEL (No Observed Adverse Effect Level) for Trimethylhexanol is 144 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
Check Trimethylhexanol compliance across multiple jurisdictions:
Related Ingredients
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