Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Trimethylhexyl Acetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 80 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 400 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Generally well-tolerated; standard IFRA guidelines apply
Regulatory Flags
Frequently Asked Questions
Is Trimethylhexyl Acetate safe in cosmetics?
Generally well-tolerated; standard IFRA guidelines apply The EU classifies Trimethylhexyl Acetate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Trimethylhexyl Acetate allowed in the EU?
Trimethylhexyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trimethylhexyl Acetate do in cosmetics?
Trimethylhexyl Acetate functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 58430-94-7.
What is the Margin of Safety for Trimethylhexyl Acetate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Trimethylhexyl Acetate?
The NOAEL (No Observed Adverse Effect Level) for Trimethylhexyl Acetate is 80 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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