Trimethylsilyl Trimethylsiloxy Salicylate

INCI: TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE

CAS Number
Not confirmed in available databases
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated; note that salicylic acid itself is an FDA-regulated OTC active

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐ŸŸก NOTABLE โ€” Hydrolysis yields salicylic acid, which is: (1) EU Annex III restricted to max 2% in cosmetics (except as preservative 0.5%); (2) prohibited in products for children under 3 years (EU); (3) an FDA OTC monograph active. Even as a pro-drug/ester, regulatory authorities may consider the salicylate exposure. Contraindicated for aspirin-sensitive individuals

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Concern Level: High

Frequently Asked Questions

Is Trimethylsilyl Trimethylsiloxy Salicylate safe in cosmetics?

๐ŸŸก NOTABLE โ€” Hydrolysis yields salicylic acid, which is: (1) EU Annex III restricted to max 2% in cosmetics (except as preservative 0.5%); (2) prohibited in products for children under 3 years (EU); (3) an FDA OTC monograph active. Even as a pro-drug/ester, regulatory authorities may consider the salicylate exposure. Contraindicated for aspirin-sensitive individuals The EU classifies Trimethylsilyl Trimethylsiloxy Salicylate as "permitted". Safety rating: MODERATE.

Is Trimethylsilyl Trimethylsiloxy Salicylate allowed in the EU?

Trimethylsilyl Trimethylsiloxy Salicylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trimethylsilyl Trimethylsiloxy Salicylate do in cosmetics?

Trimethylsilyl Trimethylsiloxy Salicylate functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in available databases.

What is the Margin of Safety for Trimethylsilyl Trimethylsiloxy Salicylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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