Tripeptide-4

INCI: TRIPEPTIDE-4

CAS Number
Not to be confused with Palmitoyl Pentapeptide-4 (CAS 214047-00-4, Matrixyl)
Function
Skin conditioning; anti-aging (collagen support)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Do NOT confuse with Pentapeptide-4 (Matrixyl) โ€” entirely different peptide; limited independent safety studies

โš ๏ธ
Concern Level: Moderate

Frequently Asked Questions

Is Tripeptide-4 safe in cosmetics?

Do NOT confuse with Pentapeptide-4 (Matrixyl) โ€” entirely different peptide; limited independent safety studies The EU classifies Tripeptide-4 as "permitted". Safety rating: MODERATE.

Is Tripeptide-4 allowed in the EU?

Tripeptide-4 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tripeptide-4 do in cosmetics?

Tripeptide-4 functions as: Skin conditioning; anti-aging (collagen support). It is classified as a cosmetic ingredient in our database. CAS number: Not to be confused with Palmitoyl Pentapeptide-4 (CAS 214047-00-4, Matrixyl).

What is the Margin of Safety for Tripeptide-4?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Tripeptide-4 in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Tripeptide-4 in your formulation.