Is Tripeptide-4 safe in cosmetics?
Tripeptide-4 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
MODERATE
Cosmetic Ingredient
Tripeptide-4
INCI: TRIPEPTIDE-4
Tripeptide-4 (CAS Not to be confused with Palmitoyl Pentapeptide-4 (CAS 214047-00-4, Matrixyl)) is a cosmetic cosmetic ingredient functioning as Skin conditioning; anti-aging (collagen support). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
CAS Number
Not to be confused with Palmitoyl Pentapeptide-4 (CAS 214047-00-4, Matrixyl)
View industrial chemical safety profile →
Function
Skin conditioning; anti-aging (collagen support)
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tripeptide-4.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Tripeptide-4 — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Tripeptide-4 allowed in the EU?
Tripeptide-4 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tripeptide-4 do in cosmetics?
Tripeptide-4 functions as: Skin conditioning; anti-aging (collagen support). It is classified as a cosmetic ingredient in our database. CAS number: Not to be confused with Palmitoyl Pentapeptide-4 (CAS 214047-00-4, Matrixyl).
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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